Middle East Technical University
Department of Engineering Sciences
06531 Ankara Turkey
E-mail: tezcaner@metu.edu.tr
Date of Birth: August, 4th, 1969
EDUCATION
B.Sc. 1991 METU, Department of Biology (Cum. GPA. 3.42)
(Graduated 2nd in a class of 50 students)
M.Sc. 1994 METU, Degree in Biotechnology (Cum. GPA. 3.40)
Thesis title: Structural stability of liposomes
Ph.D. 2001 METU in Biotechnology Programme (Cum GPA 3.69)
Thesis title: Tissue engineered retinal pigment epithelium
OTHER RELEVANT INFORMATION
Toefl Score (May 2002)
267 (computer based exam)
RESEARCH AREAS
Biomaterials Biodegradable polymers (PHBV, PLGA) liposomes, drug delivery, hard
tissue regeneration.
Tissue engineering Tissue engineering, polymeric scaffolds, surface modification
GRANTS AND SCHOLARSHIPS
2003 NATO B1 Scientific and Technical Research Council of Turkey (TUBITAK) BAYG Grant for Postdoctoral Studies (9 months, Strasbourg)
2001-2002 Scientific and Technical Research Council of Turkey (TUBITAK) BAYG Grant for Postdoctoral Studies (1 year)
2000 NATO A2 Grant from TUBITAK for research at Pasteur University, Retinopathophysiology Dept., Strasbourg, France (1 month)
1991-1992 TUBITAK, BAYG scholarship for Graduate Studies (1 year).
EXPERIENCE
March 2003 – January 2004 Postdoctoral fellow
Louis Pasteur University Dr. David Hicks’s lab (INSERM U592)
September 2002- March 2003 Instructor
(Department oF Engineering Sciences, METU)
(ES 704 Special Topics in Engineering Sciences: Tissue Engineering, ES 303 Statistical Methods for Engineers)
2001-2002 Spring Semester Postdoctoral fellow
(Department of Biological Sciences Biotechnology Research Unit)
2001-2002 Spring Semester Part time instructor
(Department of Engineering Sciences, M.E.T.U) (ES 704 Special Topics in Engineering Sciences: Tissue Engineering )
1992- 2001 Teaching assistant
(in the practicals of the Bioanalytical Chemistry (Bio 321), Cytology Laboratory (Bio 251) and Biochemistry (Bio 310) lab courses)
PUBLICATIONS
1. A. Tezcaner, K. Bugra, V. Hasırcı. Retinal pigment epithelium cultured on thin, biodegradable poly(hydroxybutyrate-co-hydroxyvalerate) films. Biomaterials 2003. 24(25):4573-83. (SCI)
2. V. Hasırcı, A. Tezcaner, Ş. Süzer. Oxygen plasma modification of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) film surfaces for tissue engineering purposes. J. Appl. Polymer Sci. 2003. 87: 1285-1289. (SCI)
3. H. Zairei, A. Borucu (Tezcaner), V. Hasırcı, E. Piskin. Imaging of liposomes by scanning tunneling microscopy. Art Cells Blood Subs. And Immob. Biotech. (1996) 24(5), 525-531. (SCI)
4. A. Tezcaner, G. Köse, V. Hasırcı. Fundamentals of Tissue engineering Tissues and Applications Technology and Health Care (2002) No. 3-4:203-216. (Index medicus, medline)
5. G. Kose, A. Tezcaner, V. Hasırcı. Fundamentals of Tissue Engineering: Carrier Materials and an Application Technology and Health Care (2002) No. 3-4:203-216. (Index medicus, medline)
6. A.Tezcaner, V.Hasırcı. Soft tissue engineering with opthalmologic applications, in Tissue Engineering and Biodegradable Equivalents eds. Lewandrowski, Wise, Trantolo, Gresser, Yaszemski, Altobelli, Marcel Dekker, Inc. NY. 2002, Ch.28, pp.545-560. (Book Chapter)
7. A. Tezcaner, V. Hasırcı. Surface properties of polymeric biomaterials and their modification for tissue engineering applications Biomaterials Handbook- Advanced Applications of Basic Sciences and Bioengineering eds. D.L. Wise, V. Hasırcı, K.U. Lewandrowski, D. E. Altobelli, D.J. Trantolo Marcel Dekker Cambridge Scientific Inc 2004, pp. 173-196. (Book Chapter)
PROJECTS
Construction of a dual system of a biodegradable mesh and collagen based bone morphogenetic protein delivery system for the treatment of bone fractures, (TBAG 2060) (2001-2002) (research associate)
Construction of bone morphogenetic protein and antibiotic loaded biodegradable polymeric controlled release systems for the treatment of bone fractures, Turkish State Planning Organisation Project. BAP07.02DPT.02K120540-12 (2002-2003) (research associate)
TUBITAK BAYG (2003) Undegraduate Students Research Grant for Elif Karagoz
Construction and characterization of a three dimensional nanofibrillar and porous PHB and PHBV8 matrices for tissue engineering applications (coadvisor)
Design of micropatterned polymeric surfaces for neo-organ preparation using nanotechnological approaches and study of their ınfluence on the proliferation, differentiation and orientation of osteoblasts (TBAG 2288) (research associate)
METU Interdisciplinary Natural and Applied Sciences Project Improvement of periosteal bone healing with Substance P loaded PHBV implants (2003-) (research associate)
METU Natural and Applied Sciences Thesis Support (BAP-2003-07-02-00-94) Development of a genetic materıal transfer approach for gene therapy (coadvisor)
METU Natural and Applied Sciences Thesis Support (BAP-2004-07-02-00-16) Cornea engineering on micropatterned surfaces (coadvisor)
Subretinal Transplantation of Tissue Engineered Retinal Pigment Epithelium, GATA Project (2003-).
Specific Targeted Research Project (STREP) Under the 6th Sixth Framework Programme for Research and Technological Development. Cornea Engineering: Three dimensional reconstruction of human corneas by tissue engineering. (Proje No:NMP2-CT-2003-504017) (research associate).
Programme of Integrated Actions (PIA-France) Bosphorus Project Micropatterned Polyelectrolyte Multilayer membranes : A Novel Approach for Retinal Pigment Epithelial Cell Grafting (2004-2005) (research associate)
MEETINGS AND WORKSHOPS
D..Şendil Keskin, A. Tezcaner, P. Korkusuz, F. Korkusuz, V Hasırcı. Evaluation of rhBMP loaded collagen/plla/saıb delivery and mesh system for repair of bone defect. 8th European Conference on Biomaterials including the 3rd Young Scientists Forum, 2003; Stuttgart, Germany.
A. Tezcaner, D.Şendil Keskin, H. Altunay, F. Korkusuz, V Hasırcı. Effect of local delivery of substance p on bone healing. BIOMED 2003; Girne- Kıbrıs.
D.Şendil Keskin, A. Tezcaner, P. Korkusuz, F. Korkusuz, V Hasırcı. Effect of rhBMP loaded collagen/plla/saıb delivery and mesh system on bone defect. BIOMED 2003; Girne- Kıbrıs
Şerife Ayaz, A. Tezcaner, A. Özkul, V. Hasırcı. Polyethylenimine as a non-viral vector. BIOMED 2003; Girne- Kıbrıs.
Ö. Çirli, A. Tezcaner, V. Hasırcı In vitro Rajı cell death effect of cısplatın loaded suprofen contaınıng photoactıve phosphatıdylcholine liposomes. BIOMED 2003; Girne- Kıbrıs.
A. Tezcaner, K. Bugra, V. Hasırcı. Retinal pigment epithelium cell culture on thin biodegradable poly (hydroxybutyrate-co-hydroxyvalerate) films. 17th European Conference on Biomaterials September 2002, Barcelona-Spain (young scientist fellowship).
D. Şendil, A.Tezcaner, V. Hasırcı Design of polymeric release systems containing bone morphogenetic protein for use in bone defects. Biomed 2002, Antalya-Turkey.
A. Tezcaner, K.Buğra, V. Hasırcı. Retinal pigment epithelium cell culture on thin biodegradable poly (hydroxybutyrate-co-hydroxyvalerate) / Sucrose Acetate Isobutyrate Films. BIOMED 8 Middle East Technical University, September 2001, Ankara-Turkey.
Hybridoma Technology Workshop (4-8 Nov. 1999) TUBITAK Research Instıtute for Genetic Engineering and Biotechnology Gebze-Turkey.
Ankara University Summer School: TEM for virology, 1-30 July 1999, Ankara.
A.Tezcaner, Y. Özden, V.Hasırcı. NATO ASI Advanced Research Workshops:Targetting of Drugs Strategies for Stealth Liposomes Cape Sounion Beach June,1996,Greece
A. (Borucu) Tezcaner, Y.Özden, V. Hasırcı. Influence of constitutents on the structural stability of liposomes12th European Conference on Biomaterials 10-13 Sept 1995, Portugal.
A.(Borucu) Tezcaner, Y. Ozden, V Hasırcı. Characterization of negatively charged liposomes 9th Symposium of Chemistry and Chemical Engineering September 1992, Trabzon-Turkey